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GLP-1 Weight Loss Calculator: Estimate Your Results

Calculate your expected weight loss on GLP-1 medications based on starting weight, medication choice, and timeline.

August 16, 2026Healthy-Weight Editorial8 min read
Medically reviewed by Dr. Sarah Chen, MD
Medically reviewed|US-licensed providers|Compounded GLP-1|No insurance needed
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Key Takeaways

  • Tirzepatide (Zepbound/Mounjaro): 22.5% average weight loss over 72 weeks — most effective
  • Semaglutide (Wegovy): 15% over 68 weeks; Ozempic: 14% over 68 weeks
  • For a 200 lb person: 45 lbs (tirzepatide), 30 lbs (Wegovy), 28 lbs (Ozempic) at max timeline
  • At 3 months: ~8% (tirzepatide), ~6% (Wegovy), ~5% (Ozempic) of starting weight
  • 10-15% of people are 'super responders'; 10-15% lose less than average

GLP-1 weight loss percentage chart

Use this chart to estimate your weight loss. Find your starting weight and timeline, then multiply by the percentage for your medication.

TimelineZepbound/MounjaroWegovyOzempic
1 month (4 weeks)2-3%2-3%1-2%
2 months (8 weeks)5%5%3%
3 months (12 weeks)8%6%5%
6 months (26 weeks)15%10%8%
1 year (52 weeks)20%13%12%
18 months (72 weeks)22.5%15%*14%*

* Wegovy and Ozempic trial data is at 68 weeks; 72-week figures are extrapolated.

Example calculations

200 lb person on Zepbound for 6 months

200 lbs x 15% = 30 lbs lost (new weight: 170 lbs)

250 lb person on Wegovy for 1 year

250 lbs x 13% = 32.5 lbs lost (new weight: 217.5 lbs)

180 lb person on Ozempic for 6 months

180 lbs x 8% = 14.4 lbs lost (new weight: 165.6 lbs)

300 lb person on Mounjaro for 18 months

300 lbs x 22.5% = 67.5 lbs lost (new weight: 232.5 lbs)

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How to use this calculator

  1. Find your starting weight in the left column.
  2. Choose your medication — Zepbound/Mounjaro (most effective), Wegovy, or Ozempic.
  3. Choose your timeline — 1, 2, 3, 6, 12, or 18 months.
  4. Multiply your weight by the percentage to estimate weight lost.
  5. Subtract from your starting weight to get your estimated end weight.

Remember: These are clinical trial averages. Individual results vary based on diet, exercise, dose, sleep, genetics, and medication adherence. About 10-15% of people lose more than average ("super responders") and 10-15% lose less.

Factors that affect your results

  • Dose: Reaching the target dose (15mg tirzepatide, 2.4mg semaglutide) is critical for maximum results.
  • Diet: High-protein, calorie-controlled diet can boost results by 30-50%.
  • Exercise: 150+ min/week of cardio + strength training significantly improves outcomes.
  • Sleep: 7-9 hours supports hormone balance and weight loss.
  • Consistency: Weekly injections as prescribed, no missed doses.
  • Starting weight: Higher starting weight generally means more total pounds lost.

Frequently asked questions

How much weight will I lose on a GLP-1 medication?

Average: Zepbound/Mounjaro 22.5% over 72 weeks, Wegovy 15% over 68 weeks, Ozempic 14% over 68 weeks. For a 200 lb person: 45 lbs, 30 lbs, 28 lbs. Individual results vary.

How is GLP-1 weight loss calculated?

Weight loss is calculated as a percentage of starting body weight. 15% loss for 200 lbs = 30 lbs (200 x 0.15). Clinical trial averages provide the percentage, but individual results vary.

How much weight can I lose on GLP-1 in 3 months?

At 3 months: ~8% on Zepbound/Mounjaro, ~6% on Wegovy, ~5% on Ozempic. For 200 lbs: 16 lbs, 12 lbs, 10 lbs respectively.

Does everyone lose the same amount on GLP-1s?

No. About 10-15% are 'super responders' who lose more than average, while 10-15% lose less. Factors: starting weight, dose, diet, exercise, sleep, genetics, adherence.

Which GLP-1 produces the most weight loss?

Tirzepatide (Zepbound/Mounjaro) at 22.5% over 72 weeks, vs semaglutide (Wegovy) at 15%. Tirzepatide is a dual GIP/GLP-1 agonist, making it more effective.

Conclusion

Use the percentage chart above to estimate your weight loss based on your starting weight, medication choice, and timeline. Remember that these are averages — your individual results may be higher or lower. The best way to maximize your results is to follow the titration schedule, eat a high-protein diet, exercise regularly, and stay consistent with your weekly injections.

Related guides

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Real patients. Real results.

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"I tried everything — keto, intermittent fasting, gym memberships. Nothing worked long-term. GLP-1 changed everything. I lost 47 pounds in 8 months and finally feel like myself again. The online process was so easy — I had my prescription in 2 days."

Jessica M., 38

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Compounded semaglutide

"At 52, my doctor said I was heading toward diabetes. I started tirzepatide through a telehealth program and lost 62 pounds. My A1C is back to normal, my blood pressure dropped, and I'm off two medications. Wish I'd done this years ago."

David R., 52

Florida

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Tirzepatide (Zepbound)

"I was skeptical about doing this online, but the whole process was professional and easy. My provider answered all my questions, and the medication arrived in 4 days. I've lost 38 pounds and finally have energy to play with my kids again."

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in 6 months

Compounded semaglutide

Results vary. These testimonials reflect individual experiences and are not typical. Weight loss depends on diet, activity, and adherence to medication.

How it works — 3 simple steps

1

Take the 60-second quiz

Answer a few questions about your health, weight goals, and medical history. It's free and confidential.

1 min

2

Meet your US-licensed provider

A board-certified clinician reviews your profile and prescribes the right GLP-1 medication for you — entirely online.

24-48 hrs

3

Get medication shipped to your door

Your prescription is filled by a US pharmacy and delivered in discreet packaging in 3-5 business days.

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Medical disclaimer: This content is for informational purposes only and is not medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any medication or weight-loss program.

Affiliate disclosure: This article contains affiliate links. We may earn a commission if you sign up through them, at no extra cost to you. This is a paid partnership. GLP-1 medications are prescription products requiring a physician consultation — not everyone qualifies, and results vary.

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