Tirzepatide Cost Per Month: $249 to $1,050 Full Price Breakdown (2026)
Complete guide to tirzepatide costs — brand-name vs compounded, insurance coverage, savings cards, and cheapest options.
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Key Takeaways
- Compounded tirzepatide: $249-$449/month through telehealth — cheapest option, no insurance needed
- Zepbound (brand): $25-$1,050/month depending on insurance and savings card
- Mounjaro (brand): $25-$1,000/month — covered for diabetes, rarely for weight loss
- LillyDirect vials: $299-$449/month — no insurance required, direct from Eli Lilly
- Eli Lilly savings card can cut Zepbound to $25/month for commercially insured patients
Tirzepatide cost per month at a glance
| Option | Monthly Cost | Insurance Required? |
|---|---|---|
| Compounded tirzepatide (telehealth) | $249-$449 | No |
| Zepbound vials (LillyDirect) | $299-$449 | No |
| Zepbound with insurance + savings | $25-$550 | Yes (commercial) |
| Zepbound without insurance | $399-$1,050 | No |
| Mounjaro with insurance (diabetes) | $25-$75 | Yes |
| Mounjaro without insurance | $950-$1,000 | No |
Compounded tirzepatide: the cheapest option
Compounded tirzepatide contains the same active ingredient as Mounjaro and Zepbound, made by FDA-registered compounding pharmacies. Through licensed US telehealth providers, it costs $249-$449/month, including consultation, prescription, medication, and shipping. No insurance required. This is 2-4x cheaper than brand-name Zepbound without insurance.
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Zepbound cost per month
Zepbound is the FDA-approved tirzepatide for weight loss. With commercial insurance and the Eli Lilly savings card, it can cost as little as $25/month. LillyDirect vials cost $299-$449/month without insurance. Retail price without insurance is $399-$1,050/month.
Mounjaro cost per month
Mounjaro is the FDA-approved tirzepatide for type 2 diabetes. With insurance, it costs $25-$75/month. Without insurance, it costs $950-$1,000/month. Mounjaro is sometimes prescribed off-label for weight loss, but insurance rarely covers it for this purpose.
Insurance coverage for tirzepatide
- Commercial insurance: Mounjaro often covered for diabetes. Zepbound coverage for weight loss varies and requires prior authorization.
- Medicare: Part D may cover Mounjaro for diabetes but generally not Zepbound for weight loss.
- Medicaid: Varies by state. Some cover for diabetes; fewer for weight loss.
- No insurance: Compounded tirzepatide at $249-$449/month or LillyDirect vials at $299-$449/month.
How to reduce tirzepatide costs
- Use the Eli Lilly savings card: Can reduce Zepbound to $25/month for commercially insured patients.
- Try compounded tirzepatide: $249-$449/month through telehealth — no insurance needed.
- Use LillyDirect: Eli Lilly's direct-to-consumer vials at $299-$449/month.
- Check formulary tiers: Ask your insurer about preferred tiers to reduce copays.
- Ask about patient assistance: Eli Lilly has a program for low-income patients without insurance.
Frequently asked questions
How much does tirzepatide cost per month without insurance?
Without insurance, brand-name tirzepatide costs $1,000/month (Mounjaro) to $1,050/month (Zepbound). Compounded tirzepatide through telehealth costs $249-$449/month. LillyDirect vials cost $299-$449/month.
What is the cheapest way to get tirzepatide?
Compounded tirzepatide through a licensed US telehealth provider, starting at $249/month. Includes consultation, prescription, medication, and shipping. No insurance required.
Does insurance cover tirzepatide?
Mounjaro is often covered for diabetes ($25-$75/month). Zepbound coverage for weight loss varies and requires prior authorization. Eli Lilly's savings card can reduce Zepbound to $25/month for commercially insured patients.
How much is Zepbound with the savings card?
The Eli Lilly savings card can reduce Zepbound to $25/month for commercially insured patients. Without insurance coverage, the card caps at $650/month. Does not work with Medicare/Medicaid.
Is compounded tirzepatide the same as Mounjaro?
Both contain tirzepatide. Mounjaro is brand-name FDA-approved for diabetes. Compounded tirzepatide is made by FDA-registered compounding pharmacies and prescribed through telehealth. Compounded costs $249-$449/month vs ~$1,000/month for Mounjaro.
Conclusion
Tirzepatide costs range from $249/month (compounded) to $1,050/month (Zepbound without insurance). With commercial insurance, the Eli Lilly savings card can bring Zepbound to $25/month. Without insurance, compounded tirzepatide or LillyDirect vials are your most affordable options.
Related guides
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