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Wegovy Injection Instructions: Step-by-Step Guide

Complete Wegovy injection guide — pen setup, dose schedule, injection sites, storage, and common mistakes to avoid.

August 16, 2026Healthy-Weight Editorial9 min read
Medically reviewed by Dr. Sarah Chen, MD
Medically reviewed|US-licensed providers|Compounded GLP-1|No insurance needed
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Key Takeaways

  • Wegovy dose schedule: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg (target), increasing every 4 weeks
  • Inject once weekly on the same day, at any time of day, with or without food
  • 3 injection sites: abdomen (2+ inches from navel), front of thigh, upper arm — rotate weekly
  • Store in refrigerator (36-46°F); in-use pen can be room temperature for up to 28 days
  • If you miss a dose: inject within 5 days, or skip if more than 5 days late — never double dose

Wegovy dose schedule

MonthDosePen Color
Month 10.25mgYellow
Month 20.5mgPink
Month 31.0mgGreen
Month 41.7mgBlue
Month 5+2.4mg (target)Black

Each dose is injected once weekly on the same day. Do not increase the dose faster than every 4 weeks.

Step-by-step Wegovy injection guide

  1. Wash your hands thoroughly with soap and water.
  2. Check the pen: Ensure the medication is clear and colorless. Check the expiration date.
  3. Remove the pen cap and wipe the rubber stopper with an alcohol swab.
  4. Attach a new needle: Remove the paper tab from the needle, screw it straight onto the pen.
  5. Remove the outer needle cap (save for disposal) and the inner needle cap (discard).
  6. Prime the pen (new pen only): Turn the dose selector to the flow check symbol. Press the start button until a drop appears at the needle tip. Repeat up to 6 times if needed.
  7. Select your dose: Turn the dose selector until the correct number appears.
  8. Choose your injection site: Abdomen, thigh, or upper arm. Clean with alcohol and let dry.
  9. Pinch a skin fold about 1 inch thick at the injection site.
  10. Insert the needle at a 90-degree angle into the pinched skin.
  11. Press and hold the start button: Hold for at least 5 seconds after the dose counter returns to 0.
  12. Withdraw the needle and release the skin fold.
  13. Remove the needle carefully and dispose of it in a sharps container. Do not recap.
  14. Replace the pen cap and store properly.
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Wegovy storage instructions

  • Before first use: Store in refrigerator at 36-46°F (2-8°C). Do not freeze.
  • After first use: Can be stored at room temperature (up to 86°F / 30°C) for up to 28 days, or continue refrigerating.
  • Do not freeze: If frozen, do not use even if thawed.
  • Protect from light: Keep the pen cap on when not in use.
  • Do not expose to heat: Keep away from direct sunlight, radiators, and car dashboards.
  • Check expiration date: Do not use expired medication.

Common Wegovy injection mistakes

  • Not priming a new pen: First use requires priming to remove air and ensure correct dosing.
  • Not holding long enough: Hold for 5+ seconds after dose counter returns to 0 to ensure full delivery.
  • Injecting through clothing: Prevents proper cleaning and increases infection risk.
  • Not rotating sites: Causes tissue irritation and inconsistent absorption.
  • Reusing needles: Increases pain, infection risk, and needle clogging.
  • Storing at wrong temperature: Heat and freezing destroy the medication.
  • Increasing dose too fast: Follow the 4-week titration schedule to minimize side effects.

Frequently asked questions

How do you inject Wegovy?

Wash hands, check pen, attach new needle, prime, select site, clean with alcohol, pinch skin, insert at 90 degrees, press and hold 5-10 seconds, withdraw, dispose needle in sharps container.

What is the Wegovy dose schedule?

Month 1: 0.25mg, Month 2: 0.5mg, Month 3: 1mg, Month 4: 1.7mg, Month 5+: 2.4mg (target). Once weekly on the same day. Do not increase faster than every 4 weeks.

Where should I inject Wegovy?

Subcutaneously in abdomen (2+ inches from navel), front of thigh, or upper arm. Rotate sites weekly. Do not inject same spot twice in a row.

How do I store Wegovy pens?

Refrigerate at 36-46°F (2-8°C). Do not freeze. In-use pen can be at room temperature (up to 86°F) for 28 days. Protect from sunlight and heat.

What happens if I miss a Wegovy dose?

If less than 5 days late, inject as soon as you remember. If more than 5 days, skip and inject on next scheduled day. Do not take two doses within 48 hours.

Conclusion

Injecting Wegovy is simple once you get the hang of it. Follow the dose schedule, rotate injection sites, store properly, and never reuse needles. If you have any questions about your injection technique, talk to your healthcare provider or pharmacist.

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Medical disclaimer: This content is for informational purposes only and is not medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any medication or weight-loss program.

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